A likelihood ratio test for changes in homeolog expression bias

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A likelihood ratio test for changes in homeolog expression bias

Gene duplications are a major source of raw material for evolution and a likely contributor to the diversity of life on earth. Duplicate genes (i.e., homeologs, in the case of a whole genome duplication) may retain their ancestral function, subor neofunctionalize, or be lost entirely. A primary way that duplicate genes may evolve new functions is by altering their expression patterns. Comparing...

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ژورنال

عنوان ژورنال: BMC Bioinformatics

سال: 2019

ISSN: 1471-2105

DOI: 10.1186/s12859-019-2709-5